HTS Corrector Publisher's description
from Vladimir Makarenkov
High-throughput screening (HTS) is an early-stage process in drug discovery which allows thousands of chemical compounds to be tested in a single study.
High-throughput screening (HTS) is an early-stage process in drug discovery which allows thousands of chemical compounds to be tested in a single study. The aim of our work was to develop and implement methods for minimizing the impact of systematic error in the analysis of HTS data. HTS-Corrector is a software application for the analysis of HTS data, detection and visualization of systematic error, corresponding correction of HTS signals, and hit selection. New methods for the statistical analysis and correction of raw HTS data are included in HTS-Corrector: background evaluation, well correction and hit selection using clustering procedures.
What's New in This Release:New features:
В· New interface
В· Chi-Square contingency test
В· Median polish and B Score correction
В· Hit selection by a fixed threshold for the whole assay
В· Hit selection by clustering methods (k-means, SASD, AICD)
В· Conversion tools
В· k-means partitioning algorithm
В· Others minors bugs
В· New version, developed using C#
System Requirements:No special requirements.
Program Release Status: New Release
Program Install Support: Install and Uninstall